慢性粒细胞白血病发生于一名毛细胞白血病患者。
Chronic myeloid leukaemia occurring in a patient with hairy cell leukaemia.
作者信息
Wandroo F A, Bareford D, el-Jehani F
机构信息
Department of Haematology, City Hospital NHS Trust, Dudley Road, Birmingham B18 7QH, UK.
出版信息
J Clin Pathol. 2000 Dec;53(12):940-1. doi: 10.1136/jcp.53.12.940.
Occurrences of second malignancies in hairy cell leukaemia are well recognised. Most of these malignancies are either solid tumours or lymphoproliferative disorders. The association of myeloproliferative disorders with hairy cell leukaemia (HCL) is very rare. This report describes a case of a patient with HCL who after remaining in remission developed Philadelphia chromosome positive chronic myeloid leukaemia (CML), which rapidly transformed to acute lymphoblastic leukaemia with further cytogenetic abnormalities.
毛细胞白血病患者发生第二原发性恶性肿瘤已得到充分认识。这些恶性肿瘤大多为实体瘤或淋巴增殖性疾病。骨髓增殖性疾病与毛细胞白血病（HCL）的关联非常罕见。本报告描述了一例HCL患者，该患者在缓解期后发生了费城染色体阳性的慢性髓性白血病（CML），并迅速转化为急性淋巴细胞白血病，伴有进一步的细胞遗传学异常。
Zotero 插件