Gleckman R
Division of Infectious Disease, St Joseph's Hospital and Medical Center, 703 Main St, Paterson, NJ 07503, USA.
Postgrad Med. 2001 Mar;109(3):87-91; quiz 28. doi: 10.3810/pgm.2001.03.877.
The newest antimicrobial drugs have broader spectrums of activity than their predecessors. But are they better than traditional antimicrobial agents? Several drugs recently approved by the US Food and Drug Administration (FDA) may be more effective against uncommon and antimicrobial-resistant pathogens, but their superior efficacy in treating common infections has yet to be proved. Dr Gleckman discusses the advantages and disadvantages of these new drugs and how they can best be used to avoid fostering the emergence of drug-resistant pathogens.
最新的抗菌药物比其前辈具有更广泛的活性谱。但它们比传统抗菌剂更好吗？美国食品药品监督管理局（FDA）最近批准的几种药物可能对罕见和耐药病原体更有效，但其在治疗常见感染方面的卓越疗效尚未得到证实。格莱克曼博士讨论了这些新药的优缺点，以及如何最好地使用它们以避免助长耐药病原体的出现。
