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[1例晚期胃癌合并肝转移患者对5-氟尿嘧啶与低剂量顺铂联合化疗反应显著,以优福定和低剂量顺铂门诊维持治疗]

[A case of advanced gastric cancer complicated with liver metastases responding remarkably to combined chemotherapy with 5-fluorouracil and low-dose cisplatin, with UFT and low-dose cisplatin for maintenance on an outpatient basis].

作者信息

Niiya F, Ikeda S, Nagata S, Iwamoto M, Shirouzu K

机构信息

Dept. of Surgery, Yanagawa Prefectual Hospital.

出版信息

Gan To Kagaku Ryoho. 2001 Mar;28(3):391-4.

PMID:11265411
Abstract

A 77-year-old man who had advanced gastric cancer with multiple liver metastases was treated by combined chemotherapy with 5-fluorouracil and low-dose cisplatin for 1 and half courses (1 course = 4 weeks). After this treatment, the primary gastric lesion was reduced, the liver metastases disappeared, and serum tumor marker levels decreased. After discharge, we administered a dose of 300 mg of UFT-E orally every day, and 10 mg of CDDP intravenously once weekly on an outpatient basis. The patient has survived with a good quality of life.

摘要

一名77岁患有晚期胃癌并伴有多处肝转移的男性患者接受了5-氟尿嘧啶和低剂量顺铂联合化疗,疗程为1个半疗程(1个疗程 = 4周)。经过该治疗后,胃部原发病变缩小,肝转移消失,血清肿瘤标志物水平下降。出院后,我们让患者门诊口服每日剂量300毫克的优福定(UFT-E),并静脉注射每周一次、每次10毫克的顺铂(CDDP)。该患者一直存活,生活质量良好。

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