Bråbäck L, Humble M
Barn- och ungdomskliniken, Sundsvalls sjukhus.
Lakartidningen. 2001 Feb 21;98(8):817-9.
Increasing numbers of reports demonstrate that low doses of ecstasy (3,4-methylenedioxymethamphetamine--MDMA) may induce life-threatening conditions, such as hyperthermia and water intoxication. These lethal states are rarely due to overdose, and young women seem to be at particular risk. This is a case report of a 20-year-old previously healthy Swedish girl. She died of water intoxication and cerebral edema approximately 24 hours after ingestion of one tablet of "ecstasy" at a rave club in Amsterdam. Clinical findings and laboratory data suggested a syndrome of inappropriate antidiuretic hormone secretion (SIADH) induced by MDMA in combination with excessive intake of water. This case illustrates the dire consequences of the present drug abuse panorama, if the increasing need for awareness of potentially lethal complications is not met within emergency health care services.
越来越多的报告表明，低剂量摇头丸（3,4－亚甲基二氧基甲基苯丙胺，即MDMA）可能引发危及生命的状况，如体温过高和水中毒。这些致命状态很少是由过量用药导致的，年轻女性似乎尤其危险。这是一例关于一名20岁瑞典女孩的病例报告。她在阿姆斯特丹一家锐舞俱乐部服用一片“摇头丸”约24小时后死于水中毒和脑水肿。临床发现和实验室数据提示，摇头丸引发抗利尿激素分泌不当综合征（SIADH），并伴有过量饮水。该病例表明，如果急诊医疗服务未能满足人们对潜在致命并发症日益增长的认知需求，当前药物滥用的局面将产生可怕后果。
