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对经鼻内接种的联合活流感病毒疫苗的免疫反应。

Immune response to combined live influenza virus vaccines administered intranasally.

作者信息

Peetermans J, Lamy F, Delem A

出版信息

Dev Biol Stand. 1975;28:340-6.

PMID:1126578
Abstract

The immune responses in volunteers vaccinated intranasally with a live influenza virus vaccine containing attenuated A and B strains have been studied. The hemagglutination-inhibiting antibody titers for both components were determined a few weeks after vaccination. They demonstrated that a good antibody response had been induced in a high percentage of volunteers. The hemagglutination inhibiting titers and percentage of seroconversion for both components were comparable to the results obtained after the intranasal administration of each component separately.

摘要

对用含有减毒 A 型和 B 型毒株的活流感病毒疫苗经鼻内接种的志愿者的免疫反应进行了研究。在接种疫苗几周后测定了两种成分的血凝抑制抗体滴度。结果表明,在高比例的志愿者中诱导出了良好的抗体反应。两种成分的血凝抑制滴度和血清转化率与分别经鼻内给予每种成分后获得的结果相当。

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