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人类链球菌感染中抗分枝杆菌相关蛋白(MAP)和抗A群碳水化合物抗体反应

The anti-MAP and anti-group A carbohydrate antibodies response in streptococcal human infections.

作者信息

Mihalcu F, Stefãnescu M

出版信息

Dev Biol Stand. 1975;28:435-8.

PMID:1126583
Abstract

The streptococcal infection cases from two outbreaks were serologically examined against two components of the streptococcal cellular wall; the M associated protein (MAP), by a latex agglutination test and the group A carbohydrate (A-CHO), by passive hemagglutination technique. Many positive cases with high levels of both antibodies were found, in rheumatic fever and glomerulo-nephritis, comparatively with the acute streptococcal infections. The differences were statistically significant. The results were correlated with the ASO titres and with the dermic cellular response.

摘要

对来自两次疫情爆发的链球菌感染病例进行了针对链球菌细胞壁两种成分的血清学检测;通过乳胶凝集试验检测与M相关蛋白(MAP),通过被动血凝技术检测A组碳水化合物(A-CHO)。与急性链球菌感染相比,在风湿热和肾小球肾炎中发现了许多两种抗体水平都很高的阳性病例。差异具有统计学意义。结果与抗链球菌溶血素O(ASO)滴度以及皮肤细胞反应相关。

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