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Blockade of tryptophan catabolism prevents spontaneous tolerogenicity of liver allografts.

作者信息

Miki T, Sun H, Lee Y, Tandin A, Kovscek A M, Subbotin V, Fung J J, Valdivia L A

机构信息

Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

出版信息

Transplant Proc. 2001 Feb-Mar;33(1-2):129-30. doi: 10.1016/s0041-1345(00)02792-5.

DOI:10.1016/s0041-1345(00)02792-5
PMID:11266740
Abstract
摘要

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Blockade of tryptophan catabolism prevents spontaneous tolerogenicity of liver allografts.色氨酸分解代谢的阻断可防止肝脏同种异体移植的自发耐受性。
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CTLA-4-Ig regulates tryptophan catabolism in vivo.CTLA-4-Ig在体内调节色氨酸分解代谢。
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