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动脉血氧分压对猴子视网膜相对血流的影响。

The effect of arterial PO2 on relative retinal blood flow in monkeys.

作者信息

Eperon G, Johnson M, David N J

出版信息

Invest Ophthalmol. 1975 May;14(5):342-52.

PMID:1126823
Abstract

The relationship of blood oxygenation to retinal blood flow has been studies in rhesus monkeys. Constriction of major retinal arteries and veins during hyperoxia and dilation during hypoxia are demonstrated. Together with mean circulation times based on the technique of fluorescein densitometry curves, these data allow an estimation of retinal blood flow, which increases considerably in hypoxia and shows a moderate decrease in hyperoxia. These findings indicate that the retinal circulation parallels that of the brain in adjusting to changes in arterial PO2 with compensatory changes in blood flow.

摘要

恒河猴的视网膜血流与血氧合作用之间的关系已得到研究。结果显示,高氧时视网膜主要动脉和静脉收缩,低氧时则扩张。结合基于荧光素密度测定曲线技术得出的平均循环时间,这些数据可用于估算视网膜血流量,低氧时血流量显著增加,高氧时则有适度减少。这些发现表明,视网膜循环在适应动脉血氧分压变化时,通过血流的代偿性变化与脑循环相似。

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