Jähnel M
Arzt für Neurologie, Psychiatrie und Psychotherapie, Krankenhaus für Psychiatrie und Psychotherapie Schloss Wemeck, Balthasar-Neumann-Platz 1, 97440 Werneck.
Nervenarzt. 2001 Mar;72(3):227-30. doi: 10.1007/s001150050743.
We report on seven geropsychiatric patients, aged 62 to 86, who had received either in- or outpatient psychiatric treatment for different disorders before being diagnosed with Huntington's disease (HD) by molecular biological methods. At the time of diagnosis, these patients presented only with mild involuntary movements in addition to other, nonspecific psychiatric symptoms such as depressive, paranoid, or dementia symptoms. In six of the seven cases, the HD symptoms had previously been misdiagnosed as tardive dyskinesia because these patients had been treated with neuroleptics in the past. Family histories were nonspecific. Three of the seven patients had family members who were described as "mentally ill" and already deceased. Huntington's disease (HD) should be considered as a differential diagnosis in geropsychiatric patients presenting nonspecific psychiatric symptoms.
我们报告了7例年龄在62至86岁之间的老年精神科患者，他们在通过分子生物学方法被诊断为亨廷顿舞蹈病（HD）之前，曾因不同疾病接受过住院或门诊精神科治疗。在诊断时，这些患者除了有抑郁、偏执或痴呆等其他非特异性精神症状外，仅表现出轻度的不自主运动。在这7例病例中的6例中，HD症状此前被误诊为迟发性运动障碍，因为这些患者过去曾接受过抗精神病药物治疗。家族史无特异性。7例患者中有3例有被描述为“患有精神疾病”且已去世的家庭成员。对于出现非特异性精神症状的老年精神科患者，应考虑将亨廷顿舞蹈病（HD）作为鉴别诊断。
