Dittrich S, Yordi L M, de Mattos A A
Fundação Faculdade Federal de Ciências Médicas de Porto Alegre (FFFCMPA), RS, Brazil.
Hepatogastroenterology. 2001 Jan-Feb;48(37):166-8.
BACKGROUND/AIMS: The aim of the present study was to evaluate the correlation between serum-ascites albumin gradient and portal pressure gradient in a population with ascites related to multiple conditions.
Thirty-seven patients were divided into two groups: group 1: 30 patients with cirrhosis as the cause of ascites, and group 2: 7 patients with ascites due to other causes. All patients were submitted to paracentesis and blood examination to determine the serum-ascites albumin gradient and the hepatic venous pressure gradient was measured.
Mean serum-ascites albumin gradient was 2.0 g/dL in group 1 and 0.6 g/dL in group 2. Mean hepatic venous pressure gradient was 14.7 mm Hg in group 1 and 1.3 mm Hg in group 2.
There was a significant correlation between the serum-ascites albumin gradient and the hepatic venous pressure gradient (r = 0.502), indicating the reliability of the serum-ascites albumin gradient in demonstrating the presence of portal hypertension and its relationship with the origin of ascites.
背景/目的：本研究旨在评估在患有多种病因所致腹水的人群中血清腹水白蛋白梯度与门静脉压力梯度之间的相关性。
37例患者被分为两组：第1组：30例因肝硬化导致腹水的患者，第2组：7例因其他原因导致腹水的患者。所有患者均接受腹腔穿刺和血液检查以确定血清腹水白蛋白梯度，并测量肝静脉压力梯度。
第1组的平均血清腹水白蛋白梯度为2.0 g/dL，第2组为0.6 g/dL。第1组的平均肝静脉压力梯度为14.7 mmHg，第2组为1.3 mmHg。
血清腹水白蛋白梯度与肝静脉压力梯度之间存在显著相关性（r = 0.502），表明血清腹水白蛋白梯度在显示门静脉高压的存在及其与腹水来源的关系方面具有可靠性。
