Mulder A H, Gerlag P G, Verhoef L H, van den Wall Bake A W
Department of Internal Medicine, St Joseph Hospital, Veldhoven, The Netherlands.
Clin Nephrol. 2001 Feb;55(2):167-70.
A 66-year-old man developed a hemolytic uremic syndrome (HUS) with acute renal failure, thrombocytopenia, fragmented red cells in the blood film and elevated serum LDH following a capnocytophaga canimorsus (DF-2) infection after a dog bite. He was treated with antibiotics, plasmapheresis and hemodialysis. Although hematologic values improved, the patient remained hemodialysis-dependent for six months. In the literature several cases of renal failure following capnocytophaga canimorsus septicemia have been described, caused by hypotension or disseminated intravascular coagulation (DIC). In our patient there were no signs of hypotension or extensive DIC. A few case reports described HUS and thrombotic thrombocytopenic purpura (TTP) following DF-2 sepsis.
一名66岁男性在被狗咬伤后感染犬咬二氧化碳嗜纤维菌(DF-2),出现了溶血性尿毒症综合征(HUS),伴有急性肾衰竭、血小板减少、血片中红细胞破碎及血清乳酸脱氢酶升高。他接受了抗生素、血浆置换和血液透析治疗。尽管血液学指标有所改善,但患者在六个月内仍依赖血液透析。文献中描述了几例犬咬二氧化碳嗜纤维菌败血症后发生肾衰竭的病例,病因是低血压或弥散性血管内凝血(DIC)。在我们的患者中,没有低血压或广泛DIC的迹象。有几例病例报告描述了DF-2败血症后发生的HUS和血栓性血小板减少性紫癜(TTP)。