Mansi I A, Opran A, Sondhi D, Ayinla R, Rosner F
Department of Medicine, Queens Hospital Center, Jamaica, New York 11432, USA.
Am J Med Sci. 2001 Mar;321(3):201-2. doi: 10.1097/00000441-200103000-00009.
We report a 55-year old woman with microscopic polyangiitis who presented with idiopathic pulmonary fibrosis and 1 year later developed hematuria and proteinuria. She had a high serum level of perinuclear anti-neutrophilic cytoplasmic antibodies. Renal angiogram was normal. The diagnosis of microscopic polyangiitis was confirmed by renal biopsy, which showed pauci-immune crescentic glomerulonephritis. The patient received immunosuppressive therapy and improved markedly. Consideration of small vessel vasculitis is important in the differential diagnosis of idiopathic pulmonary fibrosis.
我们报告了一名55岁患有显微镜下多血管炎的女性，她最初表现为特发性肺纤维化，1年后出现血尿和蛋白尿。她的血清核周抗中性粒细胞胞浆抗体水平很高。肾血管造影正常。肾活检证实为显微镜下多血管炎，显示为寡免疫性新月体性肾小球肾炎。患者接受免疫抑制治疗后明显好转。在特发性肺纤维化的鉴别诊断中考虑小血管血管炎很重要。
