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[肝细胞癌转移至额颅底]

[Metastasis in the frontal skull base from hepatocellular carcinoma].

作者信息

Kleinjung T, Held P

机构信息

Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Universität Regensburg, Franz-Josef Strauss-Allee 11, 93042 Regensburg.

出版信息

HNO. 2001 Feb;49(2):126-9. doi: 10.1007/s001060050721.

DOI:10.1007/s001060050721
PMID:11270194
Abstract

Metastatic tumours involving the nose and the paranasal sinuses are rare. Especially metastatic spread to the sphenoid sinus is an extremely rare occurrence. The most common metastatic tumour is the renal cell carcinoma. Only four cases of hepatocellular carcinoma presenting a sphenoid sinus metastasis could be found in a search of the literature. We report on the case of a 59-year-old male who suffered from a sphenoid sinus mass. A biopsy showed the tumour to be a metastatic hepatocellular carcinoma. The suspected primary tumour was then found in the left liver lobe. The early diagnosis of paranasal sinus malignancies is difficult because of the varied and nonspecific symptoms and signs. In cases of late diagnosis, the treatment is usually palliative with a poor prognosis. The importance of endoscopic examination and CT or MRI scan for early detection must be emphasized.

摘要

累及鼻和鼻窦的转移性肿瘤较为罕见。尤其是转移至蝶窦的情况极为罕见。最常见的转移性肿瘤是肾细胞癌。在文献检索中仅发现4例呈现蝶窦转移的肝细胞癌病例。我们报告一例59岁男性,其患有蝶窦肿物。活检显示该肿瘤为转移性肝细胞癌。随后在左肝叶发现了疑似原发肿瘤。由于症状和体征多样且不具特异性,鼻窦恶性肿瘤的早期诊断较为困难。在诊断较晚的病例中,治疗通常为姑息性,预后较差。必须强调内镜检查以及CT或MRI扫描对于早期发现的重要性。

相似文献

1
[Metastasis in the frontal skull base from hepatocellular carcinoma].[肝细胞癌转移至额颅底]
HNO. 2001 Feb;49(2):126-9. doi: 10.1007/s001060050721.
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Hepatocellular carcinoma with metastasis to the skull base, pituitary gland, sphenoid sinus, and cavernous sinus.肝细胞癌转移至颅底、垂体、蝶窦和海绵窦。
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Hepatocellular carcinoma presenting as sphenoid sinus metastasis.以蝶窦转移为表现的肝细胞癌。
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Hepatocellular carcinoma metastasizing to the skull base involving multiple cranial nerves.肝细胞癌转移至颅底,累及多条颅神经。
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Metastatic hepatocellular carcinoma presenting as a sphenoid sinus mass and meningeal carcinomatosis.以蝶窦肿物和脑膜癌病形式出现的转移性肝细胞癌。
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引用本文的文献

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Isolated calvarial lesion as the initial presentation of metastatic hepatocellular carcinoma: A case report and review of the literature.孤立性颅骨病变作为转移性肝细胞癌的首发表现:一例病例报告及文献复习
Surg Neurol Int. 2025 Jan 10;16:6. doi: 10.25259/SNI_507_2024. eCollection 2025.
2
Solitary skull metastasis as the first symptom of hepatocellular carcinoma: case report and literature review.孤立性颅骨转移作为肝细胞癌的首发症状:病例报告及文献复习
Neuropsychiatr Dis Treat. 2014 Apr 28;10:681-6. doi: 10.2147/NDT.S58059. eCollection 2014.
3
Isolated skull base metastasis as the first manifestation of hepatocellular carcinoma--a rare case report with review of literature.
孤立性颅底转移作为肝细胞癌的首发表现——1例罕见病例报告并文献复习
J Gastrointest Cancer. 2009;40(1-2):10-4. doi: 10.1007/s12029-009-9081-z. Epub 2009 Aug 25.
4
Unusual presentation of metastatic hepatocellular carcinoma in the nasal septum: a case report and review of the literature.鼻中隔转移性肝细胞癌的罕见表现:一例报告并文献复习
Med Oncol. 2008;25(3):264-8. doi: 10.1007/s12032-007-9028-9. Epub 2007 Nov 27.
5
Skull-base metastases.颅底转移瘤。
J Neurooncol. 2005 Oct;75(1):63-9. doi: 10.1007/s11060-004-8099-0.