Ujjin P, Wiwanitkit V, Srijindaratana G
Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Asian Pac J Allergy Immunol. 2000 Sep;18(3):177-80.
Microalb, an immunoturbidimetric test for screening urinary albumin levels was evaluated for its potential as a screening test for microalbuminuria in diabetic patients. It was compared with the current standard, the radioimmunoassay (RIA). The results showed that the test lacks sensitivity while its specificity was acceptable. Therefore, it can not replace the RIA as the screening method. This study also showed that the first early morning urine could be used if a 24- hour collection was not possible, as its albumin content fairly correlated (r = 0.78) with the 24-hour urine collection of the diabetic patients.
微白蛋白，一种用于筛查尿白蛋白水平的免疫比浊法，被评估其作为糖尿病患者微量白蛋白尿筛查试验的潜力。它与当前标准放射免疫测定法（RIA）进行了比较。结果表明，该试验缺乏敏感性，但其特异性是可接受的。因此，它不能替代RIA作为筛查方法。这项研究还表明，如果无法进行24小时尿液收集，可以使用首次晨尿，因为其白蛋白含量与糖尿病患者的24小时尿液收集结果具有相当的相关性（r = 0.78）。
