Iskenderov B G, Latyshev D S
Ter Arkh. 2000;72(11):54-6.
To study a clinical course and dynamics of arrhythmogenesis in patients with sick sinus syndrome (SSS) in varying regimes of permanent pacing.
Of 223 SSS patients, the SSS course and outcomes under pacing were studied in 148 bradyarrhythmia and 75 bradytachyarrhythmia patients. ECG variants and pacing regimes were regarded.
Within 4-13-year follow-up, constant form of supraventricular tachyarrhythmia was diagnosed in atrial stimulation in 3.4% of cases, in ventricular stimulation in 32%. Thromboembolic complications and atrioventricular blocks of the II-III degree in atrial stimulation were registered, respectively, in 5.6 and 4.2% cases. Thromboembolism in ventricular stimulation occurred in 11.1%. Reoperation (conversion from atrial to ventricular stimulation, ablation of atrioventricular conjunction) was made for change of pacing method and regime in 11.2% because of changed arrhythmia type. Total mortality for the follow-up period was 14.3%, in bradycardia--9.5%, in bradytachycardia--24%.
Continuous pacing improves quality of life in SSS patients.
研究病窦综合征(SSS)患者在不同永久起搏模式下心律失常的临床病程及动态变化。
在223例SSS患者中,对148例缓慢性心律失常患者和75例慢快综合征患者的SSS病程及起搏治疗结果进行了研究。观察了心电图变化及起搏模式。
在4至13年的随访中,心房刺激时室上性快速心律失常的持续形式在3.4%的病例中被诊断出来,心室刺激时为32%。心房刺激时血栓栓塞并发症和Ⅱ-Ⅲ度房室阻滞的发生率分别为5.6%和4.2%。心室刺激时血栓栓塞的发生率为11.1%。由于心律失常类型改变,11.2%的患者因起搏方法和模式的改变而进行了再次手术(从心房刺激转换为心室刺激、房室交界区消融)。随访期间的总死亡率为14.3%,缓慢性心律失常患者为9.5%,慢快综合征患者为24%。
持续起搏可改善SSS患者的生活质量。