Summers V K, Hipkin L J, Diver M H, Davis J C
J Clin Endocrinol Metab. 1975 May;40(5):904-6. doi: 10.1210/jcem-40-5-904.
Four men and 4 women with active acromegaly were treated with bromocryptine for 4 to 5 weeks. Serum growth hormone levels response to a glucose load were measured before and in the last weed of treatment. In only 1 patient was the grwotoh hormone response rendered normal by the drug. This patient, but none of the others, also showed an improvement in glucose tolerance and a reductin of the raised serum insulin levels during the glucose load. In three of the 8 patients vomiting was troublesome side effect of treatment.
4名患有活动性肢端肥大症的男性和4名女性接受了4至5周的溴隐亭治疗。在治疗前和治疗最后一周测量了血清生长激素水平对葡萄糖负荷的反应。仅1例患者的生长激素反应通过药物恢复正常。该患者(其他患者均未出现这种情况)在葡萄糖负荷期间还表现出糖耐量改善以及升高的血清胰岛素水平降低。8名患者中有3名出现呕吐,这是治疗带来的麻烦副作用。