Brow C S, Garcia J I, Pellegrini J E
Navy Nurse Corps Anesthesia Program, Naval Medical Center, Portsmouth, VA, USA.
CRNA. 2000 May;11(2):51-6.
A large, retrospective chart review was conducted to analyze the length of stage II labor and instrumental and cesarean-section delivery rates in nulliparous women who received either 0.0625% bupivacaine with 2 mu/mL fentanyl or 0.125% bupivacaine with 2 mu/mL fentanyl. Data collected included length of stage II labor, incidence of operative or instrumental delivery rates, concentration of bupivacaine used, and demographic data. Demographics obtained included maternal age, weight, and height, as well as neonatal gestational age, weight, and Apgar scores. Further investigated were additional analgesic requirements of supplemental boluses of local anesthetic between the groups. No differences in demographics were noted between the groups. Instrumental delivery rates were similar between the groups with an incidence of 17.5% in the 0.125% bupivacaine group versus a 15% incidence in the 0.0625% bupivacaine group. Cesarean delivery rate was 17% in the 0.125% bupivacaine group versus a 21% ratio in the 0.0625% bupivacaine group. Duration of stage II labor was noted to be prolonged in the 0.125% bupivacaine group but was not statistically significant. Based on this data, it can be concluded that the use of 0.125% bupivacaine with 2 mu/mL fentanyl does not cause a statistically significant increase in instrumental or cesarean delivery rates, nor does it have a detrimental effect on length of stage II labor.
进行了一项大型回顾性图表审查，以分析接受0.0625%布比卡因加2μg/mL芬太尼或0.125%布比卡因加2μg/mL芬太尼的初产妇第二产程的时长以及器械助产和剖宫产率。收集的数据包括第二产程的时长、手术或器械助产率、所用布比卡因的浓度以及人口统计学数据。获取的人口统计学数据包括产妇年龄、体重和身高，以及新生儿的胎龄、体重和阿氏评分。还对两组之间局部麻醉补充推注的额外镇痛需求进行了进一步调查。两组之间在人口统计学方面未发现差异。两组的器械助产率相似，0.125%布比卡因组的发生率为17.5%，而0.0625%布比卡因组的发生率为15%。0.125%布比卡因组的剖宫产率为17%，而0.0625%布比卡因组的比例为21%。0.125%布比卡因组的第二产程时长有所延长，但无统计学意义。基于这些数据，可以得出结论，使用0.125%布比卡因加2μg/mL芬太尼不会导致器械助产或剖宫产率有统计学意义的增加，对第二产程时长也没有不利影响。
