甲状腺组织组织学测量在预测原发性甲状腺毒症次全甲状腺切除术后甲状腺功能减退症方面的预测价值。
The predictive value of histometry of thyroid tissue in anticipating hypothyroidism after subtoatl thyroidectomy for primary thyrotoxicosis.
作者信息
Young R J, Beck J S, Michie W
出版信息
J Clin Pathol. 1975 Feb;28(2):94-8. doi: 10.1136/jcp.28.2.94.
Abstract
Thyroid tissue removed at partial thyroidectomy from primary thyrotoxicosis patients, after preparation for operation with carbimazole and Lugol's iodine, was studied with the histometric technique. In patients with little or no evidence of autoimmunity before operation, the chance of developing postoperative hypothyroidism was approximately 1 in 2 in those who had volume percentage of epithelium greater than 40, but only approximately 1 in 10 in those who had volume percentage of epithelium less than 40. This approach may ultimately prove of predictive value in a substantial proportion of patients for anticipating hypothyroidism after subtotal thyroidectomy for primary thyrotoxicosis.
摘要
对原发性甲状腺毒症患者在使用卡比马唑和卢戈氏碘进行术前准备后行甲状腺部分切除术所切除的甲状腺组织，采用组织测量技术进行研究。在术前几乎没有或没有自身免疫证据的患者中，上皮体积百分比大于40%的患者术后发生甲状腺功能减退的几率约为二分之一，而上皮体积百分比小于40%的患者术后发生甲状腺功能减退的几率仅约为十分之一。这种方法最终可能在相当一部分原发性甲状腺毒症患者行甲状腺次全切除术后预测甲状腺功能减退方面被证明具有预测价值。
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The predictive value of histometry of thyroid tissue in anticipating hypothyroidism after subtoatl thyroidectomy for primary thyrotoxicosis.甲状腺组织组织学测量在预测原发性甲状腺毒症次全甲状腺切除术后甲状腺功能减退症方面的预测价值。
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