Young R J, Sherwood M B, Simpson J G, Nicol A G, Michie W, Beck J S
J Clin Pathol. 1976 May;29(5):398-402. doi: 10.1136/jcp.29.5.398.
The thyroids of primary thyrotoxicosis patients prepared for partial thyroidectomy with propranolol contained much more lymphoid infiltrate than those prepared with carbimazole. No relation was found between the extent of lymphoid infiltrate in the thyroid and the development of postoperative hypothyroidism either between or within the two drug treatment groups. This study has shown that the extent of thyroid infiltrate should not be used as the major factor in predicting hypothyroidism after subtotal thyroidectomy for primary thyrotoxicosis.
用普萘洛尔准备行甲状腺部分切除术的原发性甲状腺毒症患者的甲状腺,其淋巴细胞浸润比用卡比马唑准备的患者更多。在两个药物治疗组之间及组内,均未发现甲状腺淋巴细胞浸润程度与术后甲状腺功能减退的发生之间存在关联。本研究表明,甲状腺浸润程度不应作为预测原发性甲状腺毒症甲状腺次全切除术后甲状腺功能减退的主要因素。