Ances B M, D'Esposito M
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.
Neurorehabil Neural Repair. 2000;14(3):171-9. doi: 10.1177/154596830001400302.
Stroke is a leading cause of morbidity and mortality in individuals. Many patients have good functional recovery after stroke. The mechanisms of recovery remain largely unknown. Neuroimaging of patients recovering from stroke may provide important insight into the mechanisms of recovery as well as assist in the development of new rehabilitation techniques. The first part of this article reviews previous neuroimaging studies that have monitored the reorganization within the motor and language areas after stroke. In the second section, a unifying theory based on John Hughlings Jackson's "Principles of Compensation" is presented as a possible theory for recovery of function. In the final portion of the article, possible implications and future applications of neuroimaging studies for rehabilitation are presented.
中风是导致个体发病和死亡的主要原因。许多中风患者在中风后有良好的功能恢复。恢复机制在很大程度上仍然未知。对中风后恢复的患者进行神经影像学检查，可能会为恢复机制提供重要见解，并有助于开发新的康复技术。本文的第一部分回顾了以前的神经影像学研究，这些研究监测了中风后运动和语言区域内的重组情况。在第二部分中，提出了一种基于约翰·胡克林·杰克逊“代偿原理”的统一理论，作为功能恢复的一种可能理论。在文章的最后部分，介绍了神经影像学研究对康复的可能影响和未来应用。
