Muthusethupathi M A, Rajendran S, Jayakumar M, Vijayakumar R
Department of Nephrology, Madras Medical College and Government General Hospital, Madras-600 003, Tamilnadu.
J Assoc Physicians India. 1998 Jun;46(6):526-9.
In a state-funded, live related-donor kidney transplantation programme, 616 eligible end stage renal failure (ESRF) patients were seen over a four-year period. 73% of them had potential related donors, 64% of whom were willing to donate. Fear of surgery, non-congenial pre-morbid relationships and discouragement by family members were the most common reasons for unwillingness to donate. After investigations, 76% of the willing donors were found to be fit. ABO incompatibility, lymphocyte cross-match positivity and anatomic abnormalities were the most common grounds for non-acceptance. Sixty eight percent of the willing, fit donors finally donated their kidneys, patient-death and donor-recipient withdrawal before surgery accounting for the remaining. One hundred and forty eight patients underwent renal transplantation. Two-thirds of the donors were females, mothers (37%) forming the single largest group. Eight five percent of the recipients were males. Overall, only 35% of the eligible ESRF patients had related, willing and fit donors attesting to the need for an active, cadaver-donor transplantation programme.
在一项由国家资助的活体亲属供肾移植项目中，在四年时间里共诊治了616例符合条件的终末期肾衰竭（ESRF）患者。其中73%有潜在的亲属供者，这些供者中有64%愿意捐献。害怕手术、病前关系不融洽以及家庭成员的劝阻是最常见的不愿意捐献的原因。经过检查，发现76%的愿意捐献者身体状况适合。ABO血型不相容、淋巴细胞交叉配型阳性和解剖结构异常是最常见的不被接受的原因。68%愿意且身体状况适合的供者最终捐献了肾脏，其余的原因是患者死亡以及供受者在手术前退出。148例患者接受了肾移植。三分之二的供者为女性，母亲（37%）是最大的单一群体。85%的受者为男性。总体而言，只有35%符合条件的ESRF患者有亲属、愿意且身体状况适合的供者，这证明需要一个积极的尸体供者移植项目。
