Sood A, Singh P, Midha V
Unit of Gastroenterology, Department of Medicine, Dayanand Medical College and Hospital, Ludhiana-141 001.
J Assoc Physicians India. 1998 May;46(5):454-9.
The clinical expressions, courses and consequences of hepatitis caused by different viruses (A,B,C,D,E,G) are different. Diagnosis of hepatitis is incomplete unless its etiology is specified and for chronic hepatitis, the etiology is apparent in almost all cases when autoimmune and metabolic diseases are also included. Hence, the classification based only on histology is not adequate and emphasis should also be on the etiology. The prognostic indices governing a response to interferon therapy in patients with chronic viral hepatitis have advanced with the knowledge of role played by viral genotypes, serum ferritin, hepatic iron concentration, viral quantification, and severity of histology. There have been recent changes in the definition and classification of autoimmune hepatitis as well as there is availability of newer immunosuppressive agents with encouraging results.
由不同病毒（A、B、C、D、E、G）引起的肝炎，其临床表现、病程及后果各不相同。除非明确病因，否则肝炎的诊断是不完整的；对于慢性肝炎而言，若将自身免疫性和代谢性疾病也包括在内，几乎在所有病例中病因都是明确的。因此，仅基于组织学的分类是不够的，还应强调病因。随着对病毒基因型、血清铁蛋白、肝铁浓度、病毒定量和组织学严重程度所起作用的认识不断深入，慢性病毒性肝炎患者对干扰素治疗反应的预后指标也有所进展。自身免疫性肝炎的定义和分类最近有所变化，并且有了效果令人鼓舞的新型免疫抑制剂。
