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纤维性发育不良

Fibrous dysplasia.

作者信息

Williams D M, Thomas R S

出版信息

J Laryngol Otol. 1975 Apr;89(4):359-74. doi: 10.1017/s002221510008049x.

Abstract

Three cases of monostotic fibrous dysplasia of the cranial bones are presented. Several theories of the etiology of this uncommon condition are put forward and the relationship between monostotic and polyostotic fibrous dysplasia, Albright's disease, and hyperparathyroidism is examined. The difficulty in diagnosis and the ways they may present to the ear, nose and throat surgeon are discussed. It is suggested that conservative surgery is the best mode of treatment for maxillary or temporal lesions. However, ethmoid lesions, particularly when the optic foramen or base of skull are eroded, may need a neuro-surgical approach. The use of radiotherapy in any case is deprecated.

摘要

本文报告了3例颅骨单发性骨纤维异常增殖症。提出了关于这种罕见病症病因的几种理论,并探讨了单发性和多发性骨纤维异常增殖症、奥尔布赖特氏病及甲状旁腺功能亢进之间的关系。讨论了诊断的难点以及它们可能出现于耳鼻喉科医生面前的方式。建议对上颌骨或颞部病变采用保守手术作为最佳治疗方式。然而,筛骨病变,尤其是当视神经孔或颅底受到侵蚀时,可能需要神经外科手术方法。无论如何,均不主张使用放射疗法。

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