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[颅骨纤维发育不良:神经学表现]

[Fibrous dysplasia of the skull: neurologic manifestations].

作者信息

Freitas P E, Ribeiro T R, Coutinho M F, Anicet A

机构信息

Hospital Beneficência Portuguesa, Porto Alegre, Brasil.

出版信息

Arq Neuropsiquiatr. 1989 Jun;47(2):187-91. doi: 10.1590/s0004-282x1989000200010.

Abstract

The neurological manifestations of eight patients with osseous fibrous dysplasia of skull were retrospectively studied. In this series, the frontal bone was involved in 75% of the patients, the sphenoid or temporal bones in 37.5%, and the parietal in 25%. It was observed that cranial deformities occurred in all but one case, headache was present in 87.5% of the patients, visual disturbances in 50%, proptosis in 25%, and auditive symptoms in 12.5%. Six out of the eight patients were operated on: three of the four who presented progressive visual loss had postoperative improvement. In their follow up, none presented, until now, evidence of recurrence or worsening of symptoms, confirming the benign nature of fibrous dysplasia.

摘要

对8例颅骨骨纤维异常增殖症患者的神经学表现进行了回顾性研究。在该系列中,75%的患者额骨受累,37.5%的患者蝶骨或颞骨受累,25%的患者顶骨受累。观察到除1例患者外,其余患者均出现颅骨畸形,87.5%的患者有头痛症状,50%有视觉障碍,25%有眼球突出,12.5%有听觉症状。8例患者中有6例接受了手术:4例出现进行性视力丧失的患者中有3例术后病情改善。在随访中,截至目前,无一例出现复发或症状恶化的迹象,证实了骨纤维异常增殖症的良性性质。

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