在韦恩休眠模型中诱导产生的牛分枝杆菌卡介苗蛋白质。
Proteins of Mycobacterium bovis BCG induced in the Wayne dormancy model.
作者信息
Boon C, Li R, Qi R, Dick T
机构信息
Mycobacterium Laboratory, Institute of Molecular and Cell Biology, Singapore 117609, Republic of Singapore.
出版信息
J Bacteriol. 2001 Apr;183(8):2672-6. doi: 10.1128/JB.183.8.2672-2676.2001.
Abstract
Oxygen starvation triggers the shiftdown of the obligate aerobe Mycobacterium bovis BCG to a state of dormancy. Two-dimensional electrophoresis showed a drastic up-regulation of the alpha-crystallin homolog, the putative response regulator Rv3133c, and the two conserved hypothetical proteins Rv2623 and Rv2626c in dormant bacilli.
摘要
缺氧会促使专性需氧菌牛分枝杆菌卡介苗进入休眠状态。二维电泳显示，在休眠杆菌中，α-晶状体蛋白同源物、假定的反应调节因子Rv3133c以及两个保守的假定蛋白Rv2623和Rv2626c显著上调。
相似文献
1
Proteins of Mycobacterium bovis BCG induced in the Wayne dormancy model.
J Bacteriol. 2001 Apr;183(8):2672-6. doi: 10.1128/JB.183.8.2672-2676.2001.
2
Mycobacterium bovis BCG response regulator essential for hypoxic dormancy.
J Bacteriol. 2002 Dec;184(24):6760-7. doi: 10.1128/JB.184.24.6760-6767.2002.
3
Oxygen depletion-induced dormancy in Mycobacterium bovis BCG.
J Bacteriol. 1999 Apr;181(7):2252-6. doi: 10.1128/JB.181.7.2252-2256.1999.
4
Analysis of the dormancy-inducible narK2 promoter in Mycobacterium bovis BCG.
FEMS Microbiol Lett. 2000 Jul 15;188(2):141-6. doi: 10.1111/j.1574-6968.2000.tb09185.x.
5
6
Rv3134c/devR/devS operon of Mycobacterium bovis BCG is differentially transcribed under "in vitro" stress conditions.
Tuberculosis (Edinb). 2008 Jul;88(4):273-82. doi: 10.1016/j.tube.2007.11.011. Epub 2008 Feb 1.
7
Up-regulation of narX, encoding a putative 'fused nitrate reductase' in anaerobic dormant Mycobacterium bovis BCG.
FEMS Microbiol Lett. 1999 Sep 1;178(1):63-9. doi: 10.1111/j.1574-6968.1999.tb13760.x.
8
Mycobacterial stationary phase induced by low oxygen tension: cell wall thickening and localization of the 16-kilodalton alpha-crystallin homolog.
J Bacteriol. 1998 Feb;180(4):801-8. doi: 10.1128/JB.180.4.801-808.1998.
9
Identification and characterization of mycobacterial proteins differentially expressed under standing and shaking culture conditions, including Rv2623 from a novel class of putative ATP-binding proteins.
Infect Immun. 2001 Sep;69(9):5777-85. doi: 10.1128/IAI.69.9.5777-5785.2001.
10
Reduced expression of antigenic proteins MPB70 and MPB83 in Mycobacterium bovis BCG strains due to a start codon mutation in sigK.
Mol Microbiol. 2005 Jun;56(5):1302-13. doi: 10.1111/j.1365-2958.2005.04618.x.
引用本文的文献
1
Rv0100: An essential acyl carrier protein from M. tuberculosis important in dormancy.
PLoS One. 2024 Jun 7;19(6):e0304876. doi: 10.1371/journal.pone.0304876. eCollection 2024.
2
Evidence, Challenges, and Knowledge Gaps Regarding Latent Tuberculosis in Animals.
Microorganisms. 2022 Sep 15;10(9):1845. doi: 10.3390/microorganisms10091845.
3
YTHDF3 Is Involved in the Diapause Process of Bivoltine Strains by Regulating the Expression of and Genes in the Ecdysone Synthesis Pathway.
Biomolecules. 2022 Aug 17;12(8):1127. doi: 10.3390/biom12081127.
4
Addressing Latent Tuberculosis: New Advances in Mimicking the Disease, Discovering Key Targets, and Designing Hit Compounds.
Int J Mol Sci. 2020 Nov 23;21(22):8854. doi: 10.3390/ijms21228854.
5
Modelling a Silent Epidemic: A Review of the In Vitro Models of Latent Tuberculosis.
Pathogens. 2018 Nov 15;7(4):88. doi: 10.3390/pathogens7040088.
6
Protein Composition of Differs Significantly Between Active Cells and Dormant Cells With Ovoid Morphology.
Front Microbiol. 2018 Sep 4;9:2083. doi: 10.3389/fmicb.2018.02083. eCollection 2018.
7
Delamanid Kills Dormant Mycobacteria and in a Guinea Pig Model of Tuberculosis.
Antimicrob Agents Chemother. 2017 May 24;61(6). doi: 10.1128/AAC.02402-16. Print 2017 Jun.
8
Proteomics Analysis of Three Different Strains of Mycobacterium tuberculosis under In vitro Hypoxia and Evaluation of Hypoxia Associated Antigen's Specific Memory T Cells in Healthy Household Contacts.
Front Microbiol. 2016 Sep 9;7:1275. doi: 10.3389/fmicb.2016.01275. eCollection 2016.
9
Label-free Quantitative Proteomics Reveals a Role for the Mycobacterium tuberculosis SecA2 Pathway in Exporting Solute Binding Proteins and Mce Transporters to the Cell Wall.
Mol Cell Proteomics. 2015 Jun;14(6):1501-16. doi: 10.1074/mcp.M114.044685. Epub 2015 Mar 26.
10
The DosS-DosT/DosR Mycobacterial Sensor System.
Biosensors (Basel). 2013;3(3):259-282. doi: 10.3390/bios3030259.
本文引用的文献
1
The bacteriology of respected tuberculous pulmonary lesions. 2. Observations on bacilli which are stainable but which cannot be cultured.
Am Rev Respir Dis. 1960 Sep;82:370-7. doi: 10.1164/arrd.1960.82.3.370.
2
The bacteriology of resected tuberculous pulmonary lesions. I. The effect of interval between reversal of infectiousness and subsequent surgery.
Am Rev Tuberc. 1956 Sep;74(3):376-87. doi: 10.1164/artpd.1956.74.3.376.
3
Dormant tubercle bacilli: the key to more effective TB chemotherapy?
J Antimicrob Chemother. 2001 Jan;47(1):117-8. doi: 10.1093/jac/47.1.117.
4
Bactericidal activity of nitrofurans against growing and dormant Mycobacterium bovis BCG.
J Antimicrob Chemother. 2000 Dec;46(6):917-9. doi: 10.1093/jac/46.6.917.
5
Detection of mRNA transcripts and active transcription in persistent Mycobacterium tuberculosis induced by exposure to rifampin or pyrazinamide.
J Bacteriol. 2000 Nov;182(22):6358-65. doi: 10.1128/JB.182.22.6358-6365.2000.
6
Construction and characterization of a Mycobacterium tuberculosis mutant lacking the alternate sigma factor gene, sigF.
Infect Immun. 2000 Oct;68(10):5575-80. doi: 10.1128/IAI.68.10.5575-5580.2000.
7
Characterization of a two-component system, devR-devS, of Mycobacterium tuberculosis.
Tuber Lung Dis. 2000;80(3):141-59. doi: 10.1054/tuld.2000.0240.
8
Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase.
Nature. 2000 Aug 17;406(6797):735-8. doi: 10.1038/35021074.
9
Lipid lunch for persistent pathogen.
Nature. 2000 Aug 17;406(6797):683-5. doi: 10.1038/35021159.
10
The stringent response of Mycobacterium tuberculosis is required for long-term survival.
J Bacteriol. 2000 Sep;182(17):4889-98. doi: 10.1128/JB.182.17.4889-4898.2000.
Zotero 插件