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细胞因子对体外树突状细胞培养及分化的影响。

Effects of cytokines on the culture and differentiation of dendritic cells in vitro.

作者信息

Syme R, Glück S

机构信息

Departments of Oncology, Medicine and Pharmacology & Therapeutics, Faculty of Medicine, University of Calgary, Tom Baker Cancer Centre, Calgary, Alberta T2N 4N2, Canada.

出版信息

J Hematother Stem Cell Res. 2001 Feb;10(1):43-51. doi: 10.1089/152581601750098219.

DOI:10.1089/152581601750098219
PMID:11276358
Abstract

The ability to culture dendritic cells (DC) in vitro has been integral to the dramatic increase in research in the area of immunotherapy. Over time, a number of methods for generating these cells have been developed. This article will provide an overview of the isolation and generation of DC and will give a detailed description of the role specific cytokines play in this process from the mobilization of precursors to the final maturation of DC.

摘要

体外培养树突状细胞（DC）的能力对于免疫治疗领域研究的显著增加至关重要。随着时间的推移，已经开发出多种产生这些细胞的方法。本文将概述DC的分离和产生，并详细描述特定细胞因子在这个过程中所起的作用，从前体细胞的动员到DC的最终成熟。

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