John R, Choudhri A F, Ting W, Smith C R, Rose E A, Oz M C
Department of Surgery, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Heart Surg Forum. 1998;1(1):65-70.
Minimally invasive direct coronary artery bypass grafting (MID-CABG) is being utilized for the treatment of coronary artery disease in selected patients. This innovative procedure has generated numerous technical issues relating to coronary revascularization, including whether to perform the revascularization with or without cardiopulmonary bypass (CPB).
We addressed this issue indirectly by analyzing the 1995 New York State CABG registry, comparing patients who had single vessel bypass without CPB (Non-CPB Group) to a similar cohort of patients who had CABG performed on CPB (CPB Group). The database showed stratification of patients selected for bypass grafting without CPB to a significantly higher risk group, as shown by increased age, higher incidence of reoperation, transmural MI, congestive heart failure, carotid/cerebrovascular disease, and peripheral vascular disease.
Patients in the Non-CPB Group had a higher incidence of postoperative malignant ventricular arrhythmias and heart block requiring pacemaker insertion. Otherwise, the incidence of postoperative complications was similar between the two groups.
There were no statistical differences in the hospital mortality or the length of hospitalization between the two groups. In conclusion, the data showed a definite trend toward doing higher risk cases off CPB. These cases had an acceptable early morbidity and mortality outcome. The results were comparable to a group of lower risk patients with single vessel CABG done on cardiopulmonary bypass. However, further follow-up are required to evaluate long-term outcomes and confirm the utility of this surgical option.
微创直接冠状动脉旁路移植术(MID-CABG)正被用于特定患者冠状动脉疾病的治疗。这一创新术式引发了众多与冠状动脉血运重建相关的技术问题,包括是否在体外循环(CPB)下进行血运重建。
我们通过分析1995年纽约州冠状动脉旁路移植术登记数据间接解决了这个问题,将未使用体外循环进行单支血管旁路移植的患者(非体外循环组)与一组在体外循环下进行冠状动脉旁路移植术的类似患者队列(体外循环组)进行比较。数据库显示,选择不使用体外循环进行旁路移植的患者被分层到一个风险显著更高的组,这表现为年龄增加、再次手术发生率更高、透壁心肌梗死、充血性心力衰竭、颈动脉/脑血管疾病和外周血管疾病。
非体外循环组患者术后恶性室性心律失常和需要植入起搏器的心脏传导阻滞发生率更高。否则,两组术后并发症发生率相似。
两组患者的医院死亡率和住院时间无统计学差异。总之,数据显示了在非体外循环下进行高风险病例手术的明确趋势。这些病例有可接受的早期发病率和死亡率结果。结果与一组在体外循环下进行单支血管冠状动脉旁路移植术的低风险患者相当。然而,需要进一步随访以评估长期结果并确认这种手术选择的实用性。