Radzikowska E, Głaz P
III Kliniki Gruźlicy i Chorób Płuc, Instytutu Gruźlicy i Chorób Płuc w Warszawie.
Pneumonol Alergol Pol. 2000;68(9-10):417-24.
During the last decade increasing incidence of lung cancer among women have been observed in Poland. The aim of the study was to demonstrate differences among men and women with lung cancer. Lung cancer was diagnosed in 785 female and 4619 male in 1995 in Pulmonary Outpatients Departments. Women were younger than man when all histologic types of lung cancer were analysed (59.7 vs 61.9 years p. < 0.001). Particularly younger subjects were those with adenocarcinoma and small cell lung cancer (56.9 and 57.4 years for women and for men respectively 60.2 and 59.6 years, p < 0.001). Although squamous lung cancer was the most prevalent histological type among men (43.7%) and women (24.7%), about two times higher percentage of men had this neoplasm (p. < 0.001). Adenocarcinoma (18% vs 6.6%, p. < 0.001) and small cell lung cancer (18.5% vs 15.5% p. < 0.001) were prevalent in significantly higher percentage among female than male. Nonsmokers were more frequently noticed among women then men (20.4% vs. 1.9%, p. < 0.001), particularly those with adenocarcinoma. Also women smoked less intensively (33.6 pack/years vs. 42.3 pack/years, p < 0.001) except those with squamous cancer. The higher incidence of cancer was observed among mothers (7% vs 3.8% p. < 0.001) and fathers (7.1% vs 5.6%, p. < 0.001) of women than men with lung cancer.
在过去十年中,波兰女性肺癌发病率呈上升趋势。本研究旨在揭示肺癌患者中男性和女性之间的差异。1995年,在肺部门诊确诊了785例女性肺癌患者和4619例男性肺癌患者。对所有组织学类型的肺癌进行分析时发现,女性患者比男性患者年轻(59.7岁对61.9岁,p<0.001)。腺癌和小细胞肺癌患者尤其年轻(女性分别为56.9岁和57.4岁,男性分别为60.2岁和59.6岁,p<0.001)。鳞状细胞肺癌是男性(43.7%)和女性(24.7%)中最常见的组织学类型,但男性患这种肿瘤的比例约为女性的两倍(p<0.001)。腺癌(18%对6.6%,p<0.001)和小细胞肺癌(18.5%对15.5%,p<0.001)在女性中的患病率明显高于男性。女性中不吸烟者比男性更常见(20.4%对1.9%,p<0.001),尤其是腺癌患者。除鳞状细胞癌患者外,女性吸烟强度也较低(33.6包/年对42.3包/年,p<0.001)。肺癌女性患者的母亲(7%对3.8%,p<0.001)和父亲(7.1%对5.6%,p<0.001)患癌率高于肺癌男性患者的母亲和父亲。