Janetschek G, Neumann H P
Department of Urology, University of Innsbruck, Innsbruck, Austria.
Urol Clin North Am. 2001 Feb;28(1):97-105. doi: 10.1016/s0094-0143(01)80011-2.
Because of the excessive production of catecholamines, surgery for pheochromocytoma carries a certain risk that can be reduced by accurate preoperative evaluation and by pretreatment with alpha-blockers. The authors' experience and that of other groups suggests that this inherent risk is not enhanced by the laparoscopic approach, and that, following successful surgery, patients benefit from the minimal invasiveness of this technique. Most surgeons recommend the transperitoneal approach that allows direct access to the adrenal vein, facilitating early ligation. This recommendation does not apply to other pathologies of the adrenal gland. Bilateral adrenal tumors are only seen in patients with familial pheochromocytomas. In this setting, adrenal-sparing surgery should be considered, which can also be performed laparoscopically. Previous adrenal surgery is not a contraindication but will render the procedure more difficult. Laparoscopic excision of paragangliomas is also technically feasible. Laparoscopic adrenal surgery for pheochromocytoma is a difficult and demanding task that must be performed by an experienced surgeon in cooperation with a team of specialists including an internist, endocrinologist, and anesthesiologist.
由于儿茶酚胺分泌过多,嗜铬细胞瘤手术存在一定风险,而准确的术前评估和使用α受体阻滞剂进行预处理可降低该风险。作者及其他团队的经验表明,腹腔镜手术方式并不会增加这种固有风险,而且手术成功后,患者可从该技术的微创性中获益。大多数外科医生推荐经腹途径,该途径可直接进入肾上腺静脉,便于早期结扎。此推荐不适用于肾上腺的其他病变。双侧肾上腺肿瘤仅见于家族性嗜铬细胞瘤患者。在此情况下,应考虑保留肾上腺的手术,该手术也可通过腹腔镜进行。既往有肾上腺手术史并非禁忌证,但会使手术难度增加。腹腔镜切除副神经节瘤在技术上也是可行的。腹腔镜下嗜铬细胞瘤肾上腺手术是一项困难且要求高的任务,必须由经验丰富的外科医生与包括内科医生、内分泌科医生和麻醉科医生在内的专家团队合作完成。