Moore K H, McCaughan B C
Cardiothoracic Surgical Unit, Royal Prince Alfred, Concord, New South Wales, Australia.
ANZ J Surg. 2001 Mar;71(3):143-6. doi: 10.1046/j.1440-1622.2001.02057.x.
Isolated pulmonary metastases from colorectal cancer are rare. The present study reports on the 15-year experience of the Royal Prince Alfred Unit and discusses means of improving survival outcomes.
This was a retrospective review, over a 15-year period, of 41 patients who had resectable pulmonary metastases of colorectal origin.
Most were asymptomatic at the time of diagnosis. Seventy-two per cent had solitary metastases. The most common procedure performed was a lobectomy. Median follow up was 21 months. Five-year survival was 24%. There were no significant prognostic indicators except for the ability to achieve clear surgical margins.
Morbidity and mortality have not altered significantly over time. But an improved selection process such as the use of preoperative positron emission tomography will potentially improve survival outcomes.
结直肠癌孤立性肺转移罕见。本研究报告了皇家阿尔弗雷德医院15年的经验，并探讨改善生存结果的方法。
这是一项对41例有可切除结直肠源性肺转移患者进行的为期15年的回顾性研究。
大多数患者在诊断时无症状。72%有孤立性转移。最常施行的手术是肺叶切除术。中位随访时间为21个月。5年生存率为24%。除了能够获得切缘阴性外，没有显著的预后指标。
发病率和死亡率随时间未发生显著变化。但改进选择过程，如使用术前正电子发射断层扫描，可能会改善生存结果。
