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电子束中铅屏蔽效应的量化:一项蒙特卡罗研究。

Quantifying effects of lead shielding in electron beams: a Monte Carlo study.

作者信息

Verhaegen F, Buffa F M, Deehan C

机构信息

Physics Department. Royal Marsden Hospital (Institute of Cancer Research), London, UK.

出版信息

Phys Med Biol. 2001 Mar;46(3):757-69. doi: 10.1088/0031-9155/46/3/311.

Abstract

Lead shielding in contact with the patient's skin is often encountered in radiotherapy with electron beams. The influence of the lead shielding on dose distributions in the patient cannot fully be assessed using modern treatment planning systems. In this work the problem of quantifying the effect of lead shielding on dose distributions is addressed. Monte Carlo dose calculations were performed in a half-blocked water phantom shielded by lead, using a realistic model for the fluence of an electron linear accelerator. Electron beam energies of 6-20 MeV and lead thicknesses of 1-7 mm are used for 10 x 10 cm2 and 5 x 5 cm2 fields. The perturbation of the particle fluence and dose distributions in water introduced by the lead shielding is quantified. The effect of oblique electron beams on the dose perturbation is shown. A fictitious clinical example, the shielding of an eye in electron beam treatment, is used to demonstrate the usefulness of Monte Carlo based treatment planning algorithms that can incorporate the effects of lead shielding.

摘要

在电子束放射治疗中,经常会遇到与患者皮肤接触的铅屏蔽。使用现代治疗计划系统无法完全评估铅屏蔽对患者体内剂量分布的影响。在这项工作中,解决了量化铅屏蔽对剂量分布影响的问题。使用电子直线加速器注量的真实模型,在由铅屏蔽的半封闭水模体中进行了蒙特卡罗剂量计算。对于10×10 cm²和5×5 cm²的射野,使用了6 - 20 MeV的电子束能量和1 - 7 mm的铅厚度。量化了铅屏蔽对水中粒子注量和剂量分布的扰动。展示了斜电子束对剂量扰动的影响。通过一个虚拟的临床实例,即电子束治疗中眼睛的屏蔽,来证明能够纳入铅屏蔽效应的基于蒙特卡罗的治疗计划算法的实用性

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