Weisburger E K, Ulland B M, Schueler R L, Weisburger J H, Harris P N
J Natl Cancer Inst. 1975 Apr;54(4):975-9.
Feeding 1,4-bis(fluorophenyl)-2-propynyl-N-cyclooctyl carbamate to F344 or Sprague-Dawley male rats at 125-500 ppm in the diet led to many carcinomas of the small intestine and ear duct (Zymbal's gland tumors) in addition to lymphomas and leukemias. A high incidence of mammary adenocarcinomas was found in the Sprague-Dawley rats. Only a few colon or liver tumors were observed in each strain.
在饮食中以125 - 500 ppm的剂量给F344或斯普拉格-道利雄性大鼠喂食1,4 - 双（氟苯基）-2 - 丙炔基-N - 环辛基氨基甲酸酯，除了淋巴瘤和白血病外，还导致小肠和耳道（齐默尔氏腺肿瘤）出现许多癌。在斯普拉格-道利大鼠中发现了高发性乳腺腺癌。在每个品系中仅观察到少数结肠或肝脏肿瘤。
