Laban U, Kurrasch-Orbaugh D, Marona-Lewicka D, Nichols D E
Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, IN 47907-1333, USA.
Bioorg Med Chem Lett. 2001 Mar 26;11(6):793-5. doi: 10.1016/s0960-894x(01)00062-2.
Synthesis and biological evaluation of a novel fluorinated tryptamine analogue are described. This new compound 1-(4-fluoro-5-methoxyindol-3-yl)pyrrolidine (2) was found to be a potent serotonin 5-HT1A agonist.
描述了一种新型氟化色胺类似物的合成及生物学评价。发现这种新化合物1-(4-氟-5-甲氧基吲哚-3-基)吡咯烷(2)是一种有效的5-羟色胺5-HT1A激动剂。
