Thompson R L, Summerbell C D, Hooper L, Higgins J P, Little P S, Talbot D, Ebrahim S
Institute of Human Nutrition, University of Southampton, Level B, South Academic Block, Southampton General Hospital, Southampton, Hampshire, UK, SO16 6YD.
Cochrane Database Syst Rev. 2001;2003(1):CD001366. doi: 10.1002/14651858.CD001366.
The average level of blood cholesterol is an important determinant of the risk of coronary heart disease. Blood cholesterol can be reduced by dietary means. Although dietitians are trained to provide dietary advice, for practical reasons it is also given by other health professionals and occasionally through the use of self-help resources.
To assess the effects of dietary advice given by a dietitian compared with another health professional, or the use of self-help resources, in reducing blood cholesterol in adults.
We searched The Cochrane Library (to Issue 2 1999), MEDLINE (1966 to January 1999), EMBASE (1980 to December 1998), Cinahl (1982 to December 1998), Human Nutrition (1991 to 1998), Science Citation Index, Social Sciences Citation Index, hand searched conference proceedings on nutrition and heart disease, and contacted experts in the field.
Randomised trials of dietary advice given by a dietitian compared with another health professional or self-help resources. The main outcome was difference in blood cholesterol between dietitian groups compared with other intervention groups.
Two reviewers independently extracted data and assessed study quality.
Eleven studies with 12 comparisons were included, involving 704 people receiving advice from dietitians, 486 from other health professionals and 551 people using self-help leaflets. Four studies compared dietitian with doctor, seven with self-help resources, and one compared dietitian with nurse. Participants receiving advice from dietitians experienced a greater reduction in blood cholesterol than those receiving advice only from doctors (-0.25 mmol/L (95% CI -0.37, -0.12 mmol/L)). There was no statistically significant difference in change in blood cholesterol between dietitians and self-help resources (-0.10 mmol/L (95% CI -0.22, 0.03 mmol/L)). No statistically significant differences were detected for secondary outcome measures between any of the comparisons with the exception of dietitian versus nurse for HDLc, where the dietitian groups showed a greater reduction (-0.06 mmol/L (95% CI -0.11, -0.01)). No significant heterogeneity between the studies was detected.
REVIEWER'S CONCLUSIONS: Dietitians were better than doctors at lowering blood cholesterol in the short to medium term, but there was no evidence that they were better than self-help resources. The results should be interpreted with caution as the studies were not of good quality and the analysis was based on a limited number of trials. More evidence is required to assess whether change can be maintained in the longer term. There was no evidence that dietitians provided better outcomes than nurses.
血液胆固醇的平均水平是冠心病风险的一个重要决定因素。通过饮食方法可以降低血液胆固醇水平。尽管营养师经过培训能够提供饮食建议,但出于实际原因,其他健康专业人员也会提供此类建议,偶尔还会通过使用自助资源来提供。
评估营养师提供的饮食建议与其他健康专业人员提供的建议或使用自助资源相比,在降低成年人血液胆固醇方面的效果。
我们检索了《考克兰图书馆》(至1999年第2期)、MEDLINE(1966年至1999年1月)、EMBASE(1980年至1998年12月)、护理学与健康领域数据库(1982年至1998年12月)、《人类营养》(1991年至1998年)、科学引文索引、社会科学引文索引,手工检索了关于营养与心脏病的会议论文集,并联系了该领域的专家。
比较营养师提供的饮食建议与其他健康专业人员或自助资源的随机试验。主要结局是营养师组与其他干预组之间血液胆固醇的差异。
两名评价员独立提取数据并评估研究质量。
纳入了11项研究,进行了12次比较,涉及704名接受营养师建议的人、486名接受其他健康专业人员建议的人以及551名使用自助宣传册的人。4项研究比较了营养师与医生,7项比较了营养师与自助资源,1项比较了营养师与护士。接受营养师建议的参与者血液胆固醇降低幅度大于仅接受医生建议的参与者(-0.25毫摩尔/升(95%置信区间-0.37,-0.12毫摩尔/升))。营养师与自助资源在血液胆固醇变化方面无统计学显著差异(-0.10毫摩尔/升(95%置信区间-0.22,0.03毫摩尔/升))。除了营养师与护士在高密度脂蛋白胆固醇(HDLc)方面的比较外,其他任何比较的次要结局指标均未检测到统计学显著差异,在HDLc方面,营养师组降低幅度更大(-0.06毫摩尔/升(95%置信区间-0.11,-0.01))。未检测到各研究之间存在显著异质性。
在短期至中期内,营养师在降低血液胆固醇方面比医生更有效,但没有证据表明他们比自助资源更有效。由于研究质量不高且分析基于有限数量的试验,这些结果应谨慎解读。需要更多证据来评估长期内这种变化是否能够维持。没有证据表明营养师比护士能提供更好的结局。