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女性尿失禁的阴道前壁修补术

Anterior vaginal repair for urinary incontinence in women.

作者信息

Glazener C M, Cooper K

机构信息

Health Services Research Unit (Flea), University of Aberdeen, Foresterhill Lea, Foresterhill, Aberdeen, Scotland, UK, AB25 2ZD.

出版信息

Cochrane Database Syst Rev. 2001(1):CD001755. doi: 10.1002/14651858.CD001755.

Abstract

BACKGROUND

Anterior vaginal repair (anterior colporrhaphy) is an operation traditionally used for moderate or severe stress urinary incontinence in women. About a third of adult women experience urinary incontinence.

OBJECTIVES

To determine the effects of anterior vaginal repair (anterior colporrhaphy) on stress or mixed urinary incontinence in comparison with other management options.

SEARCH STRATEGY

We searched the Cochrane Incontinence Group's trials register, and the reference lists of relevant articles. Date of most recent search: September 2000.

SELECTION CRITERIA

Randomised or quasi-randomised trials that included anterior vaginal repair for the treatment of urinary incontinence.

DATA COLLECTION AND ANALYSIS

Both reviewers independently extracted data and assessed trial quality. Two trial investigators were contacted for additional information.

MAIN RESULTS

Nine trials were identified which included 333 women having an anterior vaginal repair and 599 who received comparison interventions. A single small trial provided insufficient evidence to assess anterior vaginal repair in comparison with physical therapy. The performance of anterior repair in comparison with needle suspension appeared similar but clinically important differences could not be confidently ruled out. No trials compared anterior repair with suburethral sling operations or laparoscopic retropubic suspensions, or compared alternative vaginal operations. Anterior vaginal repair was less effective than open abdominal retropubic suspension based on patient-reported cure rates in eight trials both in the short-term (failure rate within first year after anterior repair 82/279, 29% vs 50/346, 14%; RR 1.89, 95% CI 1.39 to 2.59) and long-term (after first year, 132/322, 41% vs 68/395, 17%; RR 2.50, 95% CI 1.92 to 3.26). There was evidence from three of these trials that this was reflected in more repeat operations for incontinence (25/107, 23% vs 4/164, 2%; RR 8.87, 95% CI 3.28 to 23.94). These findings held irrespective of the co-existence of prolapse (pelvic relaxation). Later prolapse operation appeared to be equally common after vaginal (3%) or abdominal (4%) operation. In respect of the type of open abdominal retropubic suspension, most data related to comparisons of anterior vaginal repair with Burch colposuspension. The few data describing comparison of anterior repair with the Marshall-Marchetti-Krantz procedure were consistent with those for Burch colposuspension.

REVIEWER'S CONCLUSIONS: There were not enough data to allow comparison of anterior vaginal repair with physical therapy or needle suspension for primary urinary stress incontinence in women. Open abdominal retropubic suspension appeared to be better than anterior vaginal repair judged on subjective cure rates in six trials, even in women who had prolapse in addition to stress incontinence (four trials). The need for repeat incontinence surgery was also less after the abdominal operation. However, there was not enough information about post-operative complications and morbidity.

摘要

背景

阴道前壁修补术(阴道前壁缝合术)是传统上用于治疗女性中度或重度压力性尿失禁的手术。约三分之一的成年女性患有尿失禁。

目的

比较阴道前壁修补术(阴道前壁缝合术)与其他治疗方法对压力性或混合性尿失禁的疗效。

检索策略

我们检索了Cochrane尿失禁小组的试验注册库以及相关文章的参考文献列表。最近一次检索日期为2000年9月。

入选标准

纳入阴道前壁修补术治疗尿失禁的随机或半随机试验。

数据收集与分析

两位评价者独立提取数据并评估试验质量。联系了两位试验研究者以获取更多信息。

主要结果

共识别出9项试验,其中333名女性接受了阴道前壁修补术,599名接受了对照干预。一项小型试验提供的证据不足,无法评估阴道前壁修补术与物理治疗的疗效对比。与针式悬吊术相比,阴道前壁修补术的效果似乎相似,但不能完全排除临床上的重要差异。没有试验比较阴道前壁修补术与尿道下吊带手术或腹腔镜耻骨后悬吊术,也没有比较其他阴道手术。根据八项试验中患者报告的治愈率,阴道前壁修补术在短期(阴道前壁修补术后第一年失败率82/279,29% 对比50/346,14%;RR 1.89,95% CI 1.39至2.59)和长期(第一年之后,132/322,41% 对比68/395,17%;RR 2.50,95% CI 1.92至3.26)均不如开放性耻骨后膀胱悬吊术有效。这三项试验中有证据表明,这体现在尿失禁再次手术的发生率上(25/107,23% 对比4/164,2%;RR 8.87,95% CI 3.28至23.94)。无论是否存在脱垂(盆腔松弛),这些结果均成立。阴道(3%)或腹部(4%)手术后后期脱垂手术的发生率似乎相同。关于开放性耻骨后膀胱悬吊术的类型,大多数数据涉及阴道前壁修补术与Burch膀胱悬吊术的比较。少数描述阴道前壁修补术与Marshall-Marchetti-Krantz手术比较的数据与Burch膀胱悬吊术的数据一致。

评价者结论

没有足够的数据来比较阴道前壁修补术与物理治疗或针式悬吊术治疗女性原发性压力性尿失禁的疗效。根据六项试验的主观治愈率判断,开放性耻骨后膀胱悬吊术似乎优于阴道前壁修补术,即使是除压力性尿失禁外还伴有脱垂的女性(四项试验)。腹部手术后尿失禁再次手术的需求也较少。然而,关于术后并发症和发病率的信息不足。

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