Haymart M R, Allen J, Blumenthal R S
School of Nursing and School of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
J Gend Specif Med. 1999 Nov-Dec;2(6):37-42.
Relatively few studies have examined the clinical effectiveness of cholesterol-lowering drugs in women as compared with men. Most clinical trials do indicate that cholesterol lowering reduces clinical events equally effectively in both genders. However, high-density lipoprotein cholesterol and triglyceride levels may have more prognostic significance in women. The recent finding of a higher risk of death in younger women as compared with younger men who sustain a heart attack, combined with the high proportion of morbidity and mortality due to CHD in older women, emphasizes the need for a better understanding of heart disease in women. This review explores the similarities and differences between women and men regarding the management of dyslipidemia.
与男性相比，相对较少的研究考察了降胆固醇药物对女性的临床疗效。大多数临床试验确实表明，降低胆固醇对男女临床事件的减少效果相同。然而，高密度脂蛋白胆固醇和甘油三酯水平在女性中可能具有更大的预后意义。最近的研究发现，与发生心脏病发作的年轻男性相比，年轻女性的死亡风险更高，再加上老年女性中冠心病导致的高发病率和死亡率，凸显了更好地了解女性心脏病的必要性。这篇综述探讨了男女在血脂异常管理方面的异同。
