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创伤后应激障碍及其治疗的认知神经科学阐述

A cognitive neuroscience account of posttraumatic stress disorder and its treatment.

作者信息

Brewin C R

机构信息

University College London, Subdepartment of Clinical Health Psychology, UK.

出版信息

Behav Res Ther. 2001 Apr;39(4):373-93. doi: 10.1016/s0005-7967(00)00087-5.

DOI:10.1016/s0005-7967(00)00087-5
PMID:11280338
Abstract

Recent research in the areas of animal conditioning, the neural systems underlying emotion and memory, and the effect of fear on these systems is reviewed. This evidence points to an important distinction between hippocampally-dependent and non-hippocampally-dependent forms of memory that are differentially affected by extreme stress. The cognitive science perspective is related to a recent model of posttraumatic stress disorder, dual representation theory, that also posits separate memory systems underlying vivid reexperiencing versus ordinary autobiographical memories of trauma. This view is compared with other accounts in the literature of traumatic memory processes in PTSD, and the contrasting implications for therapy are discussed.

摘要

本文综述了动物条件反射、情绪与记忆的神经系统基础以及恐惧对这些系统的影响等领域的最新研究。这些证据表明,海马体依赖型和非海马体依赖型记忆形式之间存在重要区别,极端压力对它们的影响各不相同。认知科学视角与创伤后应激障碍的一种最新模型——双重表征理论相关,该理论也假定生动的重现与创伤的普通自传体记忆背后存在不同的记忆系统。本文将这一观点与创伤后应激障碍创伤记忆过程文献中的其他观点进行了比较,并讨论了其对治疗的不同影响。

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