Thomas B L, Papini M R
Department of Psychology, University of Massachusetts, Amherst, MA 01003, USA.
Physiol Behav. 2001 Mar;72(4):543-7. doi: 10.1016/s0031-9384(00)00448-0.
Experiment 1, using rats, investigated the effect of adrenalectomy (ADX) on the invigoration of lever-contact performance that occurs in the autoshaping situation after a shift from acquisition to extinction (called the extinction spike). Groups of rats with ADX or sham operations were trained under spaced and massed conditions [average intertrial intervals (ITI) of either 15 or 90 s] for 10 sessions and then shifted to extinction. ADX did not affect acquisition training but it eliminated the extinction spike. Plasma corticosterone levels during acquisition were shown in Experiment 2 to be similar in rats trained under spaced or massed conditions. Adrenal participation in the emotional arousal induced by conditions of surprising nonreward (e.g., extinction) is discussed.
实验1以大鼠为对象，研究了肾上腺切除术（ADX）对自定形情境中从习得转换到消退后杠杆接触行为增强（称为消退峰值）的影响。对接受ADX手术或假手术的大鼠组，在间隔和集中条件下（平均试间间隔分别为15秒或90秒）进行10节训练，然后转换到消退阶段。ADX不影响习得训练，但消除了消退峰值。实验2表明，在间隔或集中条件下训练的大鼠，习得期间的血浆皮质酮水平相似。文中讨论了肾上腺在由意外无奖励条件（如消退）诱发的情绪唤醒中的作用。
