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延长灭绝对大鼠工具性反应 ABC“超级更新”的影响。

The impact of prolonging extinction on the ABC "super renewal" of instrumental responses in rats.

机构信息

Universidad Nacional Autónoma de México, Mexico.

Universidad Nacional Autónoma de México, Mexico.

出版信息

Behav Processes. 2023 Jun;209:104891. doi: 10.1016/j.beproc.2023.104891. Epub 2023 May 16.

DOI:10.1016/j.beproc.2023.104891
PMID:37201661
Abstract

Two free operant conditioning experiments with rats examined the impact of conducting a large amount of extinction training on situations that enhance the ABC renewal effect (ABC super renewal). In Experiment 1, ABC renewal was strengthened by conducting acquisition in multiple contexts. All rats were trained to press a lever for food. One group was trained in one context, while the other two groups were trained in three contexts. Then, all rats received extinction in context B. For two groups this phase lasted 4 sessions, whereas it lasted 36 sessions for the other group. In Experiment 2, ABC renewal was strengthened by using a large number of acquisition sessions. Rats were trained to perform an operant response to obtain food in context A. One group received a moderate amount of training, while the rest of the rats received a larger number of acquisition sessions. Responses underwent extinction in context B. Two groups received 4 sessions, while 36 extinction sessions were used for the remaining group. In both experiments, rats were tested in context B (extinction context) and C (renewal context). Greater ABC renewal occurred both when acquisition training was conducted in multiple contexts (Experiment 1) and by increasing the amount of acquisition training (Experiment 2). Nevertheless, we found that conducting a large number of extinction sessions reduced ABC super renewal in Experiment 1 only.

摘要

两项使用大鼠进行的自由操作条件作用实验检验了进行大量消退训练对增强 ABC 复新效应(ABC 超复新)的情境的影响。在实验 1 中,通过在多个情境中进行获取来增强 ABC 复新。所有大鼠都接受了按压杠杆获取食物的训练。一组在一个情境中接受训练,而另外两组在三个情境中接受训练。然后,所有大鼠都在情境 B 中接受消退训练。对于两组大鼠,这个阶段持续了 4 个疗程,而另一组大鼠则持续了 36 个疗程。在实验 2 中,通过使用大量的获取疗程来增强 ABC 复新。大鼠接受了在情境 A 中进行操作反应以获取食物的训练。一组大鼠接受了适量的训练,而其余大鼠则接受了更多的获取疗程。在情境 B 中进行了反应消退训练。两组大鼠接受了 4 个疗程,而其余组则接受了 36 个消退疗程。在两个实验中,大鼠都在情境 B(消退情境)和 C(复新情境)中接受了测试。当在多个情境中进行获取训练(实验 1)和增加获取训练量(实验 2)时,都会发生更大的 ABC 复新。然而,我们发现,只有在实验 1 中进行大量的消退疗程会降低 ABC 超复新。

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