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采用反转恢复真稳态自由进动序列进行T(1)定量分析。

T(1) quantification with inversion recovery TrueFISP.

作者信息

Scheffler K, Hennig J

机构信息

Section of Medical Physics, Department of Diagnostic Radiology, University of Freiburg, Germany.

出版信息

Magn Reson Med. 2001 Apr;45(4):720-3. doi: 10.1002/mrm.1097.

DOI:10.1002/mrm.1097
PMID:11284003
Abstract

A snapshot FLASH sequence can be used to acquire the time course of longitudinal magnetization during its recovery after a single inversion pulse. However, excitation pulses disturb the exponential recovery of longitudinal magnetization and may produce systematic errors in T(1) estimations. In this context the possibility of using the TrueFISP sequence to detect the recovery of longitudinal magnetization for quantitative T(1) measurements was examined. Experiments were performed on different Gd-doped water phantoms and on humans. T(1) values derived from inversion recovery TrueFISP were in excellent agreement with the single-point method even for flip angles up to 50 degrees. In terms of T(1) accuracy and SNR, the proposed method seems to be superior to the conventional inversion recovery snapshot FLASH technique. Magn Reson Med 45:720-723, 2001.

摘要

单次激发快速成像(FLASH)序列可用于获取单个反转脉冲后纵向磁化恢复过程中的时间进程。然而,激发脉冲会干扰纵向磁化的指数恢复,并可能在T(1)估计中产生系统误差。在此背景下,研究了使用稳态进动快速成像(TrueFISP)序列检测纵向磁化恢复以进行定量T(1)测量的可能性。在不同的钆掺杂水模体和人体上进行了实验。即使翻转角高达50度,从反转恢复TrueFISP得出的T(1)值与单点法也非常吻合。在T(1)准确性和信噪比方面,所提出方法似乎优于传统的反转恢复单次激发FLASH技术。《磁共振医学》45:720 - 723, 2001年。

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