Mansouri B, Adybeig B, Rayegani M, Yasami S, Behshad V
Shaheed Beheshti Medical University, Tehran, Iran.
Electromyogr Clin Neurophysiol. 2001 Mar;41(2):107-15.
Fourteen patients with chronic renal failure were clinically examined and electrodiagnostically tested before and after a single session of hemodialysis. The electrodiagnostic test conducted on the ulnar sensory and the tibial motor parts indicates that the sensory and motor evoked wave amplitudes increase after dialysis (p value < 5%) but there is little change in the nerve conduction velocity. Wave amplitude is related to number of actively participating axons in neural message transference, so a decrease in amplitude means a decrease in the number of active axons involved in the neural message transfer. The present findings indicate that in the process of dialysis some of the previously inactive axons become activated. The reason for the inactivation of the axons may be due to the accumulation of toxic substances in the body as a result of renal failure. After hemodialysis, most the toxic substances are removed from the body and this leads to an increase in the number of active axons.
对14例慢性肾衰竭患者在单次血液透析前后进行了临床检查和电诊断测试。对尺神经感觉部分和胫神经运动部分进行的电诊断测试表明，透析后感觉和运动诱发电位波幅增加（p值<5%），但神经传导速度变化不大。波幅与神经信息传递中积极参与的轴突数量有关，因此波幅降低意味着参与神经信息传递的活跃轴突数量减少。目前的研究结果表明，在透析过程中，一些先前不活跃的轴突被激活。轴突失活的原因可能是由于肾衰竭导致体内有毒物质的积累。血液透析后，大多数有毒物质从体内清除，这导致活跃轴突数量增加。
