Irkeç C, Nazliel B, Koçer B
Gazi University Faculty of Medicine, Department of Neurology.
Electromyogr Clin Neurophysiol. 2001 Mar;41(2):117-22.
Clinically definite Multiple Sclerosis (MS) cases have an index greater than 0.7. Evoked potentials using geometrical patterns and click stimuli respectively and electrical stimulation of mixed nerve trunks evokes low level electrical impulses along a nerve. Prolonged latencies and changes in amplitude in these evoked potentials are thought to reflect sensory loss. This study is performed to determine whether there is a correlation between cerebrospinal fluid (CSF) findings and evoked potentials in MS during an acute MS attack. 10 male and 10 female patients' (20-55) mean (37.75) were included in to the study. They were diagnosed as definite MS with their clinical and MRI findings. During the acute attack 10 (50%) patients out of 20 had high Ig G index and one (10%) had oligoclonal band positivity. Of these 10 patients 8 (4 M, 4 F) had pathology in their evoked potentials while two had normal evoked potential findings. 8 of (80%) 10 patients whom had normal Ig G index during the acute attack had evoked potential pathology while (20%) had normal Ig G index and evoked potentials during the acute attack. Of the 8 patients which had high Ig G index and pathological evoked potential findings during acute attack were evaluated. VEP, BAEP latencies were found to be prolonged as Ig G index increased. (p < 0.05) However the same correlation can not be found with SEP parameters.
临床确诊的多发性硬化症（MS）病例指数大于0.7。分别使用几何图形和点击刺激的诱发电位以及混合神经干的电刺激会沿着神经诱发低水平电脉冲。这些诱发电位中潜伏期延长和波幅变化被认为反映了感觉丧失。本研究旨在确定急性MS发作期间脑脊液（CSF）检查结果与MS诱发电位之间是否存在相关性。研究纳入了10名男性和10名女性患者（年龄20 - 55岁，平均年龄37.75岁）。根据临床和MRI检查结果，他们被诊断为确诊MS。在急性发作期间，20名患者中有10名（50%）IgG指数升高，1名（10%）寡克隆带阳性。在这10名患者中，8名（4名男性，4名女性）诱发电位存在异常，2名诱发电位检查结果正常。急性发作期间IgG指数正常的10名患者中有8名（80%）诱发电位存在异常，而2名（20%）在急性发作期间IgG指数和诱发电位均正常。对急性发作期间IgG指数升高且诱发电位检查结果异常的8名患者进行了评估。发现随着IgG指数升高，视觉诱发电位（VEP）、脑干听觉诱发电位（BAEP）潜伏期延长（p < 0.05）。然而，体感诱发电位（SEP）参数未发现相同的相关性。
