Diaz-Cascajo C, Borghi S, Weyers W
Center for Dermatopathology, Freiburg, Germany.
Am J Dermatopathol. 2001 Apr;23(2):112-5. doi: 10.1097/00000372-200104000-00005.
Spindle cell lipoma is a benign tumor characterized by mature fatty tissue alternating with short fascicles of small spindle cells in a stroma that varies from fibrous to myxoid. The variable proportion of these elements among different examples of the neoplasm confers to spindle cell lipoma a variable microscopic appearance that can make the diagnosis difficult. Furthermore, in some instances, spindle cell lipoma may resemble liposarcoma, hemangiopericytoma, neurilemmoma, and other neoplasms representing a histopathologic pitfall. We report on two cases of spindle cell lipoma with abundant fibrous stroma reminiscence of fibroma and fibrolipoma. The name fibrous spindle lipoma is proposed for this tumor.
梭形细胞脂肪瘤是一种良性肿瘤，其特征为成熟脂肪组织与短束状小梭形细胞交替存在于从纤维性到黏液样的间质中。在肿瘤的不同病例中，这些成分的比例各不相同，这使得梭形细胞脂肪瘤具有可变的微观表现，可能导致诊断困难。此外，在某些情况下，梭形细胞脂肪瘤可能类似于脂肪肉瘤、血管外皮细胞瘤、神经鞘瘤以及其他肿瘤，这是一个组织病理学上的陷阱。我们报告了两例具有丰富纤维性间质、类似纤维瘤和纤维脂肪瘤的梭形细胞脂肪瘤病例。为此肿瘤提出“纤维性梭形脂肪瘤”这一名称。
