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空肠弯曲菌肠炎与格林-巴利综合征

Campylobacter Enteritis and the Guillain-Barré Syndrome.

作者信息

Nachamkin Irving

机构信息

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 4th Floor Gates Building, 3400 Spruce Street, Philadelphia, PA 19104-4283, USA.

出版信息

Curr Infect Dis Rep. 2001 Apr;3(2):116-122. doi: 10.1007/s11908-996-0033-5.

Abstract

Campylobacter jejuni is one of the most common causes of bacterial gastroenteritis in the United States and worldwide with approximately 2.4 million infections per year in the United States. A now clearly recognized sequelae following Campylobacter infection is the Guillain-Barré syndrome, an acute immune-mediated attack on the peripheral nervous system. How Campylobacter induces Guillain-Barré syndrome is the subject of intense investigation, and this article discusses some of the recent advances in our understanding of the clinical, epidemiologic, and pathogenic features of the disease.

摘要

空肠弯曲菌是美国及全球细菌性肠胃炎最常见的病因之一,在美国每年约有240万例感染病例。空肠弯曲菌感染后目前已明确认识到的一种后遗症是吉兰-巴雷综合征,这是一种对外周神经系统的急性免疫介导攻击。空肠弯曲菌如何诱发吉兰-巴雷综合征是深入研究的课题,本文讨论了我们在该疾病的临床、流行病学和致病特征认识方面的一些最新进展。

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