Issues in HIV/Hepatitis C Co-infection.

Co-infection of patients with hepatitis C virus (HCV) and HIV is prevalent. HCV disease is clearly exacerbated in the setting of HIV disease, and the long-term effects of HCV have become an increasing concern as patients live longer on highly active antiretroviral therapy. Although treatment for HCV disease is evolving rapidly, its role in the HIV-infected patient is not well delineated. This review will focus on the major issues in the HIV/HCV co-infected patient and discuss therapy for HCV in the era of highly active antiretroviral therapy.