利用树突状细胞及其生长因子调节免疫反应。
Modulating the immune response with dendritic cells and their growth factors.
作者信息
Pulendran B, Banchereau J, Maraskovsky E, Maliszewski C
机构信息
Baylor Institute for Immunology, Dallas, TX 75204, USA.
出版信息
Trends Immunol. 2001 Jan;22(1):41-7. doi: 10.1016/s1471-4906(00)01794-4.
Abstract
Different subsets of dendritic cells (DCs) appear to play a role in determining the specific cytokines secreted by T helper (Th) cells. A model is proposed that links together factors such as the pathogen, microenvironment, DCs and T cells in a mechanism that results in a flexible determination of T-cell polarization.
摘要
不同亚群的树突状细胞（DCs）似乎在决定辅助性T（Th）细胞分泌的特定细胞因子方面发挥作用。本文提出了一个模型，该模型将病原体、微环境、DCs和T细胞等因素以一种机制联系起来，这种机制能够灵活地决定T细胞极化。
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