Girardi E, Aloisi M S, Serraino D, Ferrara M, Lauria F N, Carballo M, d'Arminio Monforte A, Rezza G, Moroni M, Carosi G, Alessandrini A, Giacobbi D, Cremonini L, Ranieri S, Montroni M, Ippolito G
Centro di Riferimento AIDS, IRCCS "L Spallanzani," Roma, Italy.
Sex Transm Infect. 2001 Apr;77(2):130-4. doi: 10.1136/sti.77.2.130.
Specific information about determinants of sexual behaviour of HIV infected heterosexuals, like injecting drug use (IDU), are essential to design interventions aimed at promoting safer sex practices.
We analysed data on sexual behaviour collected, between March 1997 and March 1999, through a self administered questionnaire among 1050 IDUs and 642 non-IDU heterosexuals enrolled in a prospective multicentre cohort study on the natural history of HIV infection.
Among non-IDU heterosexuals, more women (48.5%) than men (25.1%) (p<0.001) reported that they were infected by HIV positive regular partners whose HIV status they were not aware of. Among the 1119 heterosexual males, one fifth reported having had more than 25 sexual partners during their lifetime. Condom use in the last sexual intercourse was more common among heterosexual IDUs (64.9%) than among non-IDU heterosexual males (58.3%) (p=0.05). Heterosexual IDU males were more likely (66.7%) than non-IDU heterosexuals (50.6%) to have an HIV negative partner (p<0.001). Of the 573 heterosexual females studied, 10.2% reported having had more than 25 lifetime sex partners. This proportion was higher among heterosexual IDUs (18.8%) than among non-IDU heterosexuals (4.3%) (p<0.001). Nearly 50% of the women in both groups reported having used a condom in the last intercourse. Almost 57% of heterosexual IDUs had a current HIV negative partner, compared with 34.9% non-IDU heterosexuals (p<0.001). In both sexes, the findings from univariate analysis were confirmed by multiple logistic regression analysis.
This study identified some important differences, in both males and females, in sexual lifestyles according to injecting drug use (for example, in terms of HIV negative partners). This observation indicates the need to tailor HIV prevention messages according to history of injecting drug use.
了解感染艾滋病毒的异性恋者性行为的决定因素的具体信息，如注射吸毒（IDU），对于设计旨在促进更安全性行为的干预措施至关重要。
我们分析了1997年3月至1999年3月期间，通过自我管理问卷收集的关于1050名注射吸毒者和642名非注射吸毒异性恋者的性行为数据，这些人参与了一项关于艾滋病毒感染自然史的前瞻性多中心队列研究。
在非注射吸毒异性恋者中，报告被艾滋病毒呈阳性的固定性伴侣感染且不知其艾滋病毒感染状况的女性（48.5%）多于男性（25.1%）（p<0.001）。在1119名异性恋男性中，五分之一的人报告其一生中拥有超过25个性伴侣。在最近一次性交中使用避孕套的情况在注射吸毒异性恋者（64.9%）中比在非注射吸毒异性恋男性（58.3%）中更为普遍（p=0.05）。注射吸毒异性恋男性比非注射吸毒异性恋者（50.6%）更有可能（66.7%）拥有艾滋病毒检测呈阴性的伴侣（p<0.001）。在研究的573名异性恋女性中，10.2%的人报告其一生中拥有超过25个性伴侣。这一比例在注射吸毒异性恋者（18.8%）中高于非注射吸毒异性恋者（4.3%）（p<0.001）。两组中近50%的女性报告在最近一次性交中使用了避孕套。近57%的注射吸毒异性恋者目前有艾滋病毒检测呈阴性的伴侣，而非注射吸毒异性恋者这一比例为34.9%（p<0.001）。在男女两性中，单因素分析的结果均得到多因素逻辑回归分析的证实。
本研究发现，根据是否注射吸毒，男女在性生活方式上存在一些重要差异（例如，在拥有艾滋病毒检测呈阴性的伴侣方面）。这一观察结果表明，需要根据注射吸毒史来调整艾滋病毒预防信息。
