Weissenberger A A, Leschek E W, Zametkin A J
National Institute of Mental Health, Bethesda, MD 20814-1276, USA.
J Am Acad Child Adolesc Psychiatry. 2001 Mar;40(3):373-6. doi: 10.1097/00004583-200103000-00018.
Familial male precocious puberty is a form of precocious puberty resulting from an activating mutation of the luteinizing hormone receptor. Behavior problems are associated with the early onset of puberty. In this case, sexual hyperactivity was treated with psychostimulants. Implications for the effectiveness of methylphenidate in reducing sexual hyperactivity with and without familial male precocious puberty are discussed, and testable hypotheses are proposed for the effects of stimulants on sexual behavior in adolescents.
家族性男性性早熟是一种由促黄体生成素受体激活突变引起的性早熟形式。行为问题与青春期过早开始有关。在这种情况下,性亢进用精神兴奋剂进行治疗。本文讨论了哌甲酯在有或没有家族性男性性早熟的情况下减少性亢进有效性的意义,并提出了关于兴奋剂对青少年性行为影响的可检验假设。