Nonpigmenting solitary fixed drug eruption after skin testing and intra-articular injection of triamcinolone acetonide.

BACKGROUND

Although several medications have been reported to cause fixed drug eruption (FDE) reactions, triamcinolone acetonide has not been previously described as an offending agent.

OBJECTIVE

To emphasize both an unprecedented causative agent and the extraordinary development of a FDE, we describe this response in a 42-year-old female patient.

METHODS

Because her history included a questionable reaction to corticosteroid preparations, prick and intradermal testing with triamcinolone acetonide was done to determine whether she could safely receive a triamcinolone acetonide injection.

RESULTS

Both skin test procedures and the intra-articular administration of triamcinolone acetonide caused FDEs on her right retroauricular area.

CONCLUSIONS

Because any drug may induce a FDE by any administration route, physicians should be aware of this delayed skin reaction when skin testing drugs.