Sener O, Caliskaner Z, Yazicioglu K, Karaayvaz M, Ozangüç N
Department of Allergy, Gülhane Military Medical Academy, Ankara, Turkey.
Ann Allergy Asthma Immunol. 2001 Mar;86(3):335-6. doi: 10.1016/S1081-1206(10)63309-1.
Although several medications have been reported to cause fixed drug eruption (FDE) reactions, triamcinolone acetonide has not been previously described as an offending agent.
To emphasize both an unprecedented causative agent and the extraordinary development of a FDE, we describe this response in a 42-year-old female patient.
Because her history included a questionable reaction to corticosteroid preparations, prick and intradermal testing with triamcinolone acetonide was done to determine whether she could safely receive a triamcinolone acetonide injection.
Both skin test procedures and the intra-articular administration of triamcinolone acetonide caused FDEs on her right retroauricular area.
Because any drug may induce a FDE by any administration route, physicians should be aware of this delayed skin reaction when skin testing drugs.
尽管已有多种药物被报道可引起固定型药疹（FDE）反应，但此前曲安奈德尚未被描述为致病药物。
为强调一种前所未有的致病因素以及FDE的特殊发展情况，我们描述了一名42岁女性患者的这种反应。
由于她的病史中包括对皮质类固醇制剂的可疑反应，因此对曲安奈德进行了点刺试验和皮内试验，以确定她是否可以安全接受曲安奈德注射。
皮肤试验程序和曲安奈德关节内给药均在她的右耳后区域引起了FDE。
由于任何药物都可能通过任何给药途径诱发FDE，因此医生在对药物进行皮肤试验时应注意这种延迟性皮肤反应。
