Melhem E R, Gotwald T F, Itoh R, Zinreich S J, Moser H W
Department of Radiology and Radiological Sciences, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
AJNR Am J Neuroradiol. 2001 Apr;22(4):773-6.
The purpose of this study was to determine whether dual-echo fast fluid-attenuated inversion recovery MR imaging and corresponding T2 brain maps can show different zones in the affected white matter of patients with cerebral X-linked adrenoleukodystrophy. Ten male patients with cerebral X-linked adrenoleukodystrophy underwent imaging performed using dual-echo fast fluid-attenuated inversion recovery and dual-echo conventional spin-echo MR sequences. Corresponding T2 relaxation maps of the brain were generated. On the basis of dual-echo fast fluid-attenuated inversion recovery images and T2 maps, the affected white matter could be divided into two distinct zones in four patients with cerebral X-linked adrenoleukodystrophy.
本研究的目的是确定双回波快速液体衰减反转恢复磁共振成像（MR成像）及相应的T2脑图谱能否显示X连锁肾上腺脑白质营养不良症患者受影响白质中的不同区域。10名患有X连锁肾上腺脑白质营养不良症的男性患者接受了使用双回波快速液体衰减反转恢复序列和双回波传统自旋回波MR序列进行的成像检查。生成了相应的脑T2弛豫图谱。基于双回波快速液体衰减反转恢复图像和T2图谱，在4名患有X连锁肾上腺脑白质营养不良症的患者中，受影响的白质可分为两个不同的区域。
